Sorry about the delayed reply - been busy with non-computer stuff.
I'm afraid I went ahead and hit delete all, but there seems to have been no fall-out so far. After that scan finished (Avast found another 500-odd infected files), I rebooted, and the laptop seemed fine. Next, I did a safe-mode scan with MBAM, and that came back clear too.
I gave the laptop back to my friend, and, touch wood, it's been fine so far - no warnings of further infected files, and no blue-screens or anything. Sorry, I should have thought to copy the last Avast log over to this (my) machine, but I forgot.
There's still the problem of the .NET framework updates failing, but my friend was nagging me for his machine back :-) If there are any further problems, I'll empty the chest first before scanning, and if Ramnit makes a comeback, I'll post again.
Many thanks for your help essexboy - it's much appreciated by both me and my friend.
Cheers, Jon.