For my setup, only Comodo CIS(Without AV), Avast5 and Window Defender are realtime, the rest(Spybot, spywareblaster, mbam & Superantispyware) are all on-demand, they are not auto-start with window. my system seem to be functioning properly, no slowdown, redirected webpage or popup, in short i did not notice any abnormal behavior from my system. I had been using avast4 b4 this and it had never detected the threat that avst5 did.
I had just installed Avast5(B4 this is using Avast4) on my brother's pc which is also running comodo cis(no av) and window defender, when using custom scan it also show the exact same infection threat. Below is the Log taken from the custom scan log
Process 1120 [cmdagent.exe], memory block 0x0000000000F80000, block size 90112 [L] Win32:Agent-KXV [Drp] (0)
Process 1120 [cmdagent.exe], memory block 0x0000000008C10000, block size 843776 [L] Win32:Delf-DNW [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000003D80000, block size 262144 [L] Win32:Adloader-AC [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000003ED0000, block size 262144 [L] Win32:FraudLoad-P [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000004050000, block size 262144 [L] Win32:Agent-SG [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x00000000040A0000, block size 262144 [L] Win32:PcClient-OD [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000004130000, block size 262144 [L] Win32:Baidubar-B [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x00000000041E0000, block size 262144 [L] Win32:Small-HZH [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x00000000042C0000, block size 262144 [L] Win32:Banker-CDW [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000004320000, block size 262144 [L] Win32:Agent-CWD [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000004390000, block size 262144 [L] BV:AutoRun-E [Wrm] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000004490000, block size 262144 [L] JS:Agent-AU [Expl] (0)
Process 1176 [msmpeng.exe], memory block 0x0000000004560000, block size 397312 [L] Win32:Small-HUF [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x00000000045E0000, block size 262144 [L] Win32:Small-gen2 [Trj] (0)
Process 1176 [msmpeng.exe], memory block 0x00000000046A0000, block size 262144 [L] Win32:Zbot-AVH [Trj] (0)