If I can just jump in, here, I have experience of doing the same sort of thing (different program) then working out why it wouldn't run.
You will probably need to delete the folder for Avast (Alwil) completely from where you copied it to. A program can not be "copied" to another drive; it needs to be installed to that drive.
(There are quite a few processes that are added during the install, including to the registry, the "documents and settings" folder, and others. Worst case scenario with me was I had to do a complete computer and registry search to remove the relevant entries for the program I'd tried to move in this fashion, before it would install correctly again.
If you have to do this, especially search for entries that include the path to the location you copied it to.)
Similar to what DavidR posted, slightly different words.