I installed new video card, upon powering up Avast again said I was unprotected.
I did a clean boot, no services other than Microsoft's, no start-up programs.
Manually started Avast, said unprotected. Clicked Start, 1 minute count down window popped up after 10 or so seconds asking if I wanted to perform that action, answered Y, nothing happened. Ran the OTL again, it's attached.