this has been an epidemic for my 100 PC client base with 3 of my client's servers. a few before the client 7 upgrades which were really bad, BSOD on boot until I uninstalled or at least uninstalled the sandbox component.
since the 7 upgrades, there are no BSOD but just the waiting forever part which is not fun for me when they call wondering why they can't login at 7am (after I have spent all night doing server maintenance). I am pretty annoyed about this after this morning I had to reboot a SBS 2003 server and I left it starting up for 2 hours (walked away) and it became hung at "preparing network connection". after two resets I uninstalled the Avast client in safe mode which still had Sandbox installed, rebooted and it started ok. because of the normal wait times of booting a SBS server the trial and error resolution time was about 3 hours! 3 hours wasted which ended up eating into morning production, costing real money to the customer!!!!
I reinstalled without the sandbox and it is fine. so far, in every instance, removing the sandbox resolved the issue. I think the sandbox is a great idea but on a server, it causes more troubles than it solves (even stopped a Blackberry server service from starting!!??). I would like to see it as an option instead of a default on server client installs; not to mention the Sharepoint shield not starting on 100% of servers I manage.