What OS/SP ? Win10 OS Build 15063.138 (1703)
What exact version of avast ? Program Verson 17.3.2291 ---- Virus Definition 170504-0
Is there any other security (related) software installed ? No other Security Software beside Default Win10 (Windows Defender)
Already performed a repair of avast ? Yes (it was reinstall after i installed Win10)
Already performed a clean installation with the latest avast version ? Yes (when i reinstalled Win10)
Seems like i'm not only one having the issue ... according to the people who build the addon ... they have said
""" Remember to make backups of your WTF folder. (Or just WTF/Account/AccountName/SavedVariables/WeakAuras.lua). There are several reports that seem to indicate that Avast Antivirus prevents World of Warcraft from properly writing that file and thus entirely wiping all auras. Also, if wow crahes or disconnects while in a loading screen/shutdown, there's a small chance that it will wipe out all auras. MAKE A BACKUP NOW
Edit: It's now confirmed that Avast Antivirus Gaming Mode is preventing World of Warcraft from properly writing the settings files for Addons and crashing wow.(edited) """""
That is taken right from there Discord