1. Files that can't be scanned are just that, not an indication they are suspicious/infected, just unable to be scanned.
Many programs (usually security based ones) password protect their files for legitimate reasons, there are others (and avast doesn't know the password or have any way of using it even if it did know it).
2. By examining 1) the file name, 2) reason given by avast! for not being able to scan the files, 3) the location of the files, you can get an idea of what program they relate to. You may need to expand the column headings to see all the text.
If you can give some examples of those file names, the locations and reason given why it can't be scanned might help us further ?
Though I suspect given the problem you won't be able to access this information.
I recall there has been a recent topic related to this issue with on-demand scans, this since the latest program update, but I can't find it or recent/similar.