I know Avast should give an Alert, as should Comodo. I don't think that it is Avast alone, but some sort of conflict that began on the day I updated to 6.0.1203.
Yes, I am using Defense+, and Comodo sandbox, but I have the Avast sandbox & webrep disabled. I downloaded the MSE uninstaller from thewebatom.net, not sure I needed it for MSE, it seems to have uninstalled ok on it's own but maybe there were some reg entries remaining.
As far as exclusions, I have added the entire Avast folder as trusted files in D+ and All Avast executables have full rights in firewall. Not sure what exclusions I would make in Avast. I know I followed the Malwarebytes forum instructions for excluding avast in both MBAM & AVast, but I'm not sure what exclusions I would set for Comodo. They've always got along ok before. Strangely enough it's not all .exe's that won't download either, just the Comodo and Acronis files that I mentioned so far (and Admuncher updates) Downloaded the files at work, so the links are ok. I have disabled all shields, MBam,Admuncher and tried with no success.