Personally, I hardly believe that some of them must be generic names that automatically generate by generic detection, no more no less.
For example, on machine infected by VBS/Redlof (polymorphic/encrypted Visual Basic Script virus) avast! detect most of them as
VBS:Redlof but some of them detected as
VBS:Malware [Script] 
. It just like Macro virus created by some virus generator and most of them would detected as Macro virus.gen (detected by some kind of generic/family detection). But I haven't seen something like Win32:Worm-gen. {UPX!}, it would be great if avast! can detect some or most of ITW worms by its generic detection like Trojan-like
But that's just my guess, I may be completely wrong.