Same deal here. Except I went to last kown good config, so Vista64 works OK, but now avast won't start 3 services; File system, IM and P2P. Hope it's a quick bug fix.
I turned on the Windows fire wall for now.
UPDATE: In spite of the fact that avast self-updated less than 2 hours ago, and screwed up somehow, I elected to try manual updating, and voila, it works now. Mystified why the automatic update didn't work in the first place. Have used product for a few years. This is the first time I've had any problem at all.