Hi pancakegeorge,
I to wondered about laying out the $ for BART at first, but it has paid for it's self in the speedof job turnaround.
RE the Reg hack, I was refering to the case that some worms modify the registry. These changes need to be reversed in some cases, and my understanding is that the AV removal is just of the detected files.
There little apps out there (Blaster removal tool) for the complete removal of certain worms, Blaster for instance. As well as remving the files, it also removes the registry keys placed or changed by the worm.
So as far as plugins, I use the added feature in BART2 of "add your own directory" to BART. In this area I place a number of worm removal tools, for specific worms. I make a note of the worms, delete them with BART and run the specific removal tool for that worm.
The Reg cleaner looks for invalid or orphan registary keys and enables them to be removed. It does not have anything to do with virus removal (my understanding). A clean registry is like a clean desk. Makes things easier to work with. It will keep wiindows stable too.
As far as 100% detection, I would say it has once so far failed to detect a w32 worm. Not bad for concidering I use BART almost daily. Factors in this can be the level of detection you have it set to. The in-depth can take a long time on large drive, so I may have had the level to low in that case.
Hopefully we can get a spyware detection package into BART as well as a startup manager. This will make life easier to clean infected machines.
I like to clean as much off as I can before having to boot back into windows.
BART is good and getting better. It's very hard to make 1 package that is all things to all people. Ask for want you want, and it may happen.

I would say that if you need to work on WIN2K onward machines on a daily basis, this is for you.
Feel free to ask away

w0mbat