Unfortunately Lukor is currently on a vacation so I guess I'll follow up.
I think he tested it here with 4mbit uplink.
alanrf is suggesting that the problem does not appear when using OE as email client (that is, with OE, it is always slow - no matter if avast is installed or not). Is that statement valid even on your machine?
Also, do I understand it correctly that you're getting these results even with outbound scanning disabled. What if you uninstall the Internet Mail provider completely - does that make any difference? And other providers...?
Somehow, we still don't know what component is causing the problem, exactly... 
Cheers
Vlk
I have tried it uninstalling the components with the same results. If outbound scanning is disabled and/or pertinent components uninstalled, I still only get about 83KBS (kilobytes/sec) transfer rate (35KBS with Avast outbound email scanning enabled).
Even if I uninstall Avast completely, I still only get about 83 KBS. As I indicated in a previous post, I now have re-installed NAV 2004 and, amazingly, my outbound email speeds (with NAV outbound scanning enabled) is back up to 92KBS.
This would seem to imply that the NAV installation either fixed some bad registry entries created by Avast and/or NAV somehow handles transmissions more effectively. My guess is some registry settings (or equivalent) were "fixed" since I always get around 92KBS upload speeds when I test with various speed sites regardless of what AV is installed.
This is a very strange situation.
Also, FWIW:
1. I am using the Mozilla 1.7.8 email client
2. Several other individuals on a Comcast site also see the same problem.
I appreciate your looking into this.
Thanks,
Harvey