Ok, I tried that and it didn't work as expected.
I do have two additional exclusions, the folder containing eicar test files and windows prefetch files (.pf).
However, I decided to delete everything as you suggested (I could always put them in again) and closed the window. When I opened it again, yes ?:\PageFile.sys was there but the others I mentioned previously (what I thought were the default set, see below) were gone.
C:\WINDOWS\TEMP\*.TMP
C:\WINDOWS\TEMP\_AVAST4_\UNP*
C:\WINDOWS\WINSXS\*.MANIFEST
C:\WINDOWS\WINSXS\*.CAT
C:\WINDOWS\WINSXS\*.POLICY
So it would appear that there is something in the mix not working as expected or should those file exclusions above not the default?