I have a theory as to what is going on with my machine that may help track the issue.
Bearing in mind I have successfully installed the patch and that my issues intermittent I think it may be down to the timing of logging in after boot up.
My machine is a windows 8.1 laptop that is using the quick shutdown/startup. The go slows/profile issues seem to occur if I do not login instantly the machine has booted, also the problems seem not to occur if I wait a minute or so after booting.
So I am guessing there is a point during startup when windows/Avast are doing things and if you happen to login at that point you will get go slows/default profiles/etc.....
Just a theory but with over 30 years as a software developer myself I know every little clue helps