They relate to emergency update executable to download an install emergency updates, whilst the files are uniquely identified they will be the same size.
Personally I would leave these files in the emupdate folder alone.
You may see other folders under the setup folder which are named in the same way. Personally I feel these should be cleaned by avast housekeeping. But I have been regularly deleting these sub-folders without issue, you have o disable the avast self-defence module to be able to do so - ensure you enable it after - The choice is yours on what action to take, generally I leave the most recent uniquely named sub-folder.