Well, I cannot fix the problem...
But I figured out some things... It seems only a problem when I start up my computer. I guess Avast starts before the Sygate icon appear, and I guess this will be the problem. If I am fast and start outlook before sygate appears in the tray I get an error in outlook too that it cannot download the email.
Is there a manner to start sygate in front of avast?
Thanks for all your replies, I appreciate it!
VinzZ