I was thinking it might be servers.def being 0KB in size, if that is the case, delete it. There is also a servers.def.lkg (last known good), that to may be 0KB as that is use if there is a problem with servers.def.
Try a repair of avast. Add Remove programs, select 'avast! Anti-Virus,' click the Change/Remove button and scroll down to Repair, click next and follow. You need to be on-line to do this. Then check the size of the servers.def file, mine is 7.36MB and has 52 servers listed.