Yes, agree with Eddy. I have Macrium free as well, but no issues. However, I did not upgrade to the new version, I completely wiped Avast from my systems first (Safe Mode), then used their tool as a secondary check for removal (Safe Mode) and then rebooted to a normal system. Installed the latest and no issues.
FYI, I had massive issues when installing over an older version; network issues, Firefox, CCleaner, Thunderbird, Steam, etc. Safest bet, do the above and be happy.