I have used both Norton (for almost 5 years), and McAfee for a trial. I never had an issue with either, and according to AV Comparatives both have a higher detection rate than Avast.
However, I prefer Avast and am using the Home version on my laptop. It has never had any compatibility issues. FWIW I am using KAV6 on my desktop, and will buy it when it is for sale. I like the detection rates of KAV.
It may seem inconsistent, but I am planning to keep Avast free on my laptop, and together with Ewido I think the degree of protection does not suffer in comparison with other top AVs. I like Avast, and have recommended it, and installed it on several computers including my daughter's. None have had an infection.
Hope this helps from a non-geek that has Avast and other AV, and likes them both.
Jerry