The same thing happened to me with Window 7 Pro. Adobe Reader DX and SnagIt both stopped working. Whenever I'd try to open them I'd get "Windows cannot find 'c:\.....\AcroRd32.exe' or Windows cannot find 'c:\.....\snagit.exe'. I thought I had a virus and ran both Avast and Malwarebytes, both of which showed no infection. I tried uninstalling and reinstalling both programs. Nothing helped. Until, today, when I googled "Windows cannot find Acrobat reader" and found the answer on the Adobe forums:
https://forums.adobe.com/thread/2262502"AdorobatCorrect Answer
by Adorobat on Jan 13, 2017 5:48 AM
Could you please try the following steps:
1- Close Reader
2- Hold down Windows key and press R on your keyboard, this will bring up Run dialogue box.
3- Type regedit in the run dialogue box and hit Enter, click Yes when User Account Control pop-up appears.
4- Navigate to HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\Image File Execution Options, delete the key AcroRd32.exe
5- Relaunch Reader"
As Alan.Cart discovered, the debug values for both had been set to C:\Program Files\AVAST Software\Avast Cleanup\autoreactivator.exe
I followed the procedure for both Acrobat Reader and Snagit and now both are running perfectly. I also checked to make sure those were the only keys affected.
I uninstalled Avast Cleanup after the first time I ran it because I noticed that it deleted or deactivated quite a few things. Fortunately, I had created a System restore point before running it and was able to repair most of the damage that Cleanup had created. Except, apparently the debug value problems.