Hi Pete, it seems something keeps killing our app in the background - when it happens, Avast loses "Accessibility permission", which makes the Chrome protection stop working. You are probably using some power saving mode or a task killer app, or you have disabled the Avast Permanent Notification (in Settings > Notifications).
The solution is to whitelist our app from such booster or task killer, but if it doesn't help or you cannot find it, please let me know what device you have (manufacturer, type, Android version). Thanks.