Regardless whether or not you do an system image in case of disaster, in the case of the scenario above, if you install Avast first and then image your system, and after that install MWB, and find they don't work well together or not at all, restoring your system to Avast only is a snap. Windows 10 natively supports disk imaging.
You can restore your system in less than 10 minutes using that image if you have the latest hardware.
FYI, Malwarebytes is currently working on a fix for a driver conflict MWB/Avast.