Depending on your permissions, yes, that's normal. Process Manager may still throw an error if a program is working correctly. Process Manager also does not by default launch with Admin rights.
It is worth noting that certain files (like wscript.exe) are commonly marked as malicious, but aren't generally. I'm using wscript for two reasons here. THe first being you specifically mentioned it, and two, I'm famaliar with wscript. In some infections, (notably, USB key infections), they'll use wscript.exe to launch their script. However, the script is elsewhere (typically a hidden file on a USB key and or host system). When you force end wscript, you stop the infection, but the source still exists. The moment you plug an infected USB in, or restart, it'll come right back. In essence, you removed the symptom, but not the root issue. Process Explorer offers the ability to Verify Files from all major sources (Microsoft, Google, NVIDIA, Intel, AMD etc) as well as scan those processes files on VirusTotal. (Take the results of VirusTotal with a grain of salt sometimes. They do occasionally alert on legitimate files such as BitTorrents.)
If you're concerned about infections, I'd recommand you follow the steps
here.
