Scanning Interface:
1. Spyware and Adweare Scanning and removal.
2. Security or
Immunization (see picture). Right now:
27591 spyware items could be immunizated. Compare with Spybot only: 14362.
1575 infected websites are access-blocked.
529 tracing cookies are monitored.
One minor handicap: the
enabling procedure is very time consuming compared to SpyBot and even IE-Spyad (adding protection to Windows Registry).
Prevention is the solution! 
3. Registry Scan: cleaning the registry for invalid items. There is a
white list (ignore list). It's not the 'best' registry cleaner we can found. But, as a lot of users like, safer than powerful...
4. System Analysis: recommend tweak settings and 'false' empty registry keys solution.
5. Startup items: with 'trust it' feature. You can manage all your startup items and/or Registry keys (for advanced users).
6. Privacy Sweep: could be improved... few plugins and programs target. Oh, a handicap: does not allow cookie management... I can loggoff of avast forums

7. Temporary files cleaning: Temporary Files from Windows, Internet Explorer and/or Recycle bin. Allow some configurability. Miss the 'timed' features of IEPrivacy cleaner (that allow you to delete temporary files after some 'days' of safety).
8. The on-line scanning?
http://www.trendmicro.com/hc_intro/default.asp Well, it takes you to TrendMicro
