I'm a newbie in the forum, faced the same problem, and since the conversation ends without concrete solution, so this might help because I think I found the solution to this.
This problem occurs after an unsuccessful updating process, whether the automatic update when the Avast! U3 loads, or when it's done manually through the program console. I experienced the problem because the internet connection here is SO BAD, it disconnects randomly from every 5 hour, to every 2 minutes. Everytime I failed downloading the update, the Avast program failed to load afterwards.
So I tried to simulate the disconnection by going to a very good hotspot with an excellent connection, update the Avast, and interrupt the process by disabling the wifi device . . . the same problem came. I tried it once more : Reinstalling it, putting in the license key, update it and interrupt the process. Same thing. So I tried to reinstalled it again, and updated it without interruption. No problem. And the next two days, I went back to the hotspot, update and interrupt it again, same problem came back. So I conclude, it is the interrupted updating process. So guys, when you want to update the virus definitions, you might consider to find a good internet connection, or else, you have to download the 31 megs of initial update all over again. With a T1 connection, it should be no problem . . . but those with dial-ups, it's hell
