I have neither noticed anything. Sure I have seen sometimes that there are unprotected items, but not sure what caused them.
Only, SpyBot's update system, sometimes it hangs and I need to stop the program from Task Manager is really annoying. Plus it takes too much CPU when scanning and that teatimer that is not even running now, was also a resource hog.
Has been at least a month since I used SpyBot last time, might take a look to see if it is behaving. It used to save me by letting stupid Kazaa from startup in something like 3 years ago. Then it was usefull.
And then MS antispyware deleted all my songs I had downloaded, hehe. I had Kazaa uninstalled, but the songs were in that directory, so it quaranteened it or something, but I could not get them back. What can one say of usefullness of that MS antispyware beta, if it quaranteened a folder with no programs there left. Might have gotten better, but not running it either.