I am still being unclear so, for that, I apologize.
I understand what WS does but what is the process that a file gets sent to 'Quarantine?'
Files that get sent to quarantine are for the most part detected by the file system shield, something on your system or something you are copying to your system could be infected.
The File Shield scans, all New, Modified or Executed files before they are allowed to be saved (new file) or modified or run. If they are found to be infected then they will be sent to the Quarantine/Virus Chest. Typically this is for files that are active (can be run, e.g. executable files) or files that can run. Also if you have a zip (compressed) and you try to open/run that files that are extracted would be scanned before being allowed to be saved to your system.
There really is nothing to worry about the circumstances of the why and wherefores they would be quarantined as it isn't something that happens without your knowledge. Avast Would first Alert you to a malware problem and display a screen with the information, for most instances the default action would be to send them to quarantine.
The above is pretty much the default action, unless you change the Core Shield settings and I wouldn't recommend that, a more experienced user may elect to be notified (ASK) and they make the decision on the action to be taken.