What is the infected file name, where was it found e.g. (C:\windows\system32\infected-file-name.xxx) ?
Check the avast! Log Viewer (right click the avast icon), Warning section, this contains information on all avast detections.
You can adjust both the size of the avast chest and the max file size, right click the avast icon, Program Settings, Chest.
You could also check the offending/suspect file at:
VirusTotal - Multi engine on-line virus scanner Or
Jotti - Multi engine on-line virus scanner if any other scanners here detect them it is less likely to be a false positive.
You can't do this with the file in the chest, you will need to move it out.If it is indeed a false positive, add it to the exclusions lists (
Standard Shield, Customize, Advanced and Program Settings, Exclusions) and periodically check it (scan it in the chest), there should still be a copy in the chest even though you restored it to the original location. When it is no longer detected then you can also remove it from the Standard Shield and Program Settings, exclusions.
Also see
(Mini Sticky) False Positives, how to report it to avast! and what to do to exclude them until the problem is corrected.