This has no doubt been asked and answered somewhere here a zillion times in the past (maybe I was even involved), but I'm too old and lazy to set up a proper search.
On rare occasions, probably when there's something major come through from MS Update, I'll see additional copies of one or more of the system files (3 files, on my XP system) added to the chest.
Assuming I do regular scans and my system is very likely clean, is it safe to assume I can delete from the chest the older copy/copies of such system file duplicates?