That is good in that the file has been analysed as if it was simply the URL that you gave, in the VT tests the Web Shield scan on live sites can't be run.
So you could possibly override the Avast Alert Exception for the download location to download but not run the file.
Now the File System Shield, should kick in and alert. It could be sent to quarantine and from there submitted to avast for analysis.
Giving details on it and possibly this topic and or the virustotal results.
It may even be because the file isn't digitally signed given what I would consider a low grade alert FileRepMalware [Misc].