Unless you have a robust Back-up and Recovery Strategy (didn't seem so in your previous experiences), then I would suggest leaving your restless hands at more productive things.
There is malware that doesn't so much cross the virtual to physical boundary, but is aparently able to avoid the virtual environment.
It also depends on the virtual environment you are using, the settings that you have set, some allow to save bookmarks, etc. to the real drive and if you have any similar setting that would be a chink in the armour. I guess the malware you come into contact with is a big factor as it would have to be one that is able to avoid the virtual environment, before you ask, I don't know.