Try the cure first, but (no guarantees, like all things in life) there are times when even that doesn't work as this uses encryption to try and stop it from being repaired and vitro is another stage up from virut which DrWeb had some reasonable success with.
Many find that once it get a grip you are fighting an uphill battle, so it is important to salvage what you can, to make any re-installation less painful.
Like data files, like documents, spreadsheets, emails, email account details, registration keys, address book, favourites/bookmarks, downloaded files/programs, etc. the list goes on and on but if you don't want to lose it back it up. There are many back-up programs that can simplify this task and run it every day.
Some have gone down the scorched earth policy with an fdisk (low level disk format), followed by the format (fat32/NTFS, etc.) and then re-installation. Fortunately I have never had to go down that path, so I haven't a great deal of practical experience. I know it was bad enough when I got this system almost a year ago when the only thing on it was the OS, but I was well prepared and not under this kind of duress.
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Pre-emptive measures for the future:
I would suggest you also look disk imaging software. I use Drive Image 7.1, the last version by PowerQuest before it was bought by Symantec and merged into its Norton Ghost disk imaging software, another option is Acronis true Image, there are others, most of them are paid options.
I take an image back-up of my primary hard disk partitions every week as part of my system maintenance. This is saved to my second HDD or it can also be written to a DVD. I also back-up volatile data files, .doc, .xls, etc. along with emails, bookmarks, address book, registration keys, etc. (anything you don't want to lose) every day sometimes several times a day.
So if I experience a problem like yours (haven't to date) then I just restore my last back-up disk image (takes about 15 minutes) followed by the last daily data back-up (takes seconds rather than minutes) and I will have lost virtually nothing.
Compare that with your experience and the money I paid for my disk imaging software would have paid for itself if it had to be used just once if you valued your time at just £5 per hour. I have had to use it several times (not virus related) where it has hauled my a** out of the fire, it is an absolute god send.