My guess whatever is causing your issue will be gone when you upgrade to Windows 7.
Who are the publishers of those files in the file properties? Are they Microsoft driver files or replaced by something else?
i have Another suspect
i8042prt.sys all drivers belong to microsoft.
I'm sure, when i upgrade to Windows 7 that will be fixed
Theory.I think that somehow avast is forcing the drivers.
should be a combination of avast and other drivers, probably when they correct the high DPC latency in malwarebites these problems may reduce or stop.
that is why nobody can reproduce what happens to me, each computer has a specific configuration and different drivers.
NON.I got this driver of the mouse and keyboard
i8042prt.sys it is not causing high DPC latency but high ISR.
my mouse its usb end i unplug him,but not work with me.
I hope fix your problem soo.
I'll keep searching one by one, but if my theory is correct only avast can improve the system.
I think it is night in Japan,good night.