it's not just about malware. You may indeed browse safely and live well without noscript, although s**t can happen, on hacked sites (legit sites whose owner aren't aware they got hacked), and NS would protect, but that was not my point here: my point is that AB+ like NoScript have one point in common: they block the ad and stat (-ware) channels; they avoid you to be tracked indefinitely...and privacy matters. The one hundred percent privacy shield doesn't exist yet, and hey you still need to browse the Internet, but NS can reduce the impact, and does in fact continuously reduce the impact of unwanted traffic, intrusions etc...nothing that could harm your system, but still, I do mind. You can browse the web with NS and be blocking thousands of useless crap without you noticing any loss of "relevant" info through the pages you visit.
There's a downside, without that crap, no free internet. But too much is too much...do a test, run Fiddler2 (Microsoft) and see the traffic with NS/AB+ and then without...see the tracking at work, that's purely disgusting. Now if you don't mind "double click" and "analytics" etc... watching behind your back - and that's no paranoia, that's exactly what they do - so if you're unaware, or if you don't mind or may be if you can just look the other way and smile stupidly (nothing personal), then indeed, Noscript is not for you.