O.K. I did the such procedure.
1. I double-clicked on OTLPE icon
2. In a pop-up window I selected c:\windows as a windows folder
3. In next window "Do you wish to load remote user profile(s)" I choose "yes"
4. I chose one profile from a list (it was impossible to choose more)
and left "Automatically Load All Remaining Users" checked is it was already.
5. OTL started.
6a. I tried to drag and drop scan.txt to the "Custom Scans/Fixes" box
7a. It says "Error! Not a valid fix file"
6b. I tried to double click on "Custom Scans/Fixes". And in new window, that has opened, I tried to change location to find my desktop where I previously saved scan.txt.
7b. It wrote: "Error! Access violation at address 7CA0936 in module 'SHELL32.dll'. Read of address 00000006" and crashed
8. I opened the file in notepad.exe and copied Ctrl+A, Ctrl+C and pasted Ctrl+V (or otherwise I simply rewrote it).
9. I pressed Run Scan button
10. It proceeded for some time and when it came to: "Manual File Scan - Getting folder structure..." it poped up: "Error! out of memory"
There is one more thing. It does detect my USB-disc (after sticking it into, there pops an icon in sys-tray "Safely Remove Hardware", but sometimes it don't show it in My computer). To copy scan.txt I use command-line:
copy e:\scan.txt b:\documents and settings\default user\desktop\
It has generally some problems with file system. Maybe you have previous version?