O.K, done all suggested and I am already running malwarebites and it found no problems before and now.
I downloaded Avast and installed it on my wife's PC(yes, it's official copy from Avast's web site).
2~3 minutes after install, system locked-up solid to where I needed to reboot...
Booted into "safe mode", attempted "last known good config" and rebooted...locked-up solid yet again!
Reboot again in "safe mode", uninstalled Avast via "add remove program" and system back to normal
Opened "regedit" and deleted any and all entries relating to Avast.
I'm done with Avast for my wife's PC...don't know what the heck is wrong but, it's very frustrating and annoying not to mention time consuming task to keep doing same things over & over again.
I'll just find the latest anti-virus OTHER THAN Avast and try it out for my wife's PC...Avast just don't work!
My PC is running just fine with Avast so, it will remain as is
Thanks for all the suggestions and assistance.