@tuhis,
Avast has its conflicts; I don't deny it (at all). But if you can't boot into Windows Safe Mode in *any* of those computers, I would tend to think that Avast is not the direct main problem (although I haven't discarded it, since I have no real proof of it being "innocent" nor "guilty").
What I could also say is that there are other common items between those systems you are building that could also be as suspicious as Avast (and probably more, but that's my personal guess).