After reading the above post I tried something similar. . . .
C:\Users\Bob\Downloads\autosandboxme.exe -> program just runs, i.e. no Autosandbox prompt nor red outline
C:\autosandboxme.exe -> program just runs, same as above
F:\autosandboxme.exe -> prompt from Autosandbox appears, and program has red outline when run as it should
Hopefully this helps identify where the problem might be . . . .
EDIT: same thing happens when using OTL.exe as the test file