If after updating Avast you cannot send email over a certain size, this is how I fixed the "Avast Problem". Its not a Firewall issue, its not a email client issue, its an Avast issue. I tried everything that these forums suggested and nothing worked.
So, I uninstalled the newest version and reinstalled 40.211 and guess what, the email works great - again.
I am running WinXP, ZoneAlarm on a AMD64 machine. I use Thunderbird .9. I tried using OE, Netscape and other clients and nothing would work. That is until I reverted to the older version of Avast.
Avast is a great AV program, but I feel that my experience proves that it is an issue with the updated Avast program.