Not sure if this exclusion "C:\Windows\Microsoft.NET\Framework\*.*" would do what you want. That would only exclude files in the "C:\Windows\Microsoft.NET\Framework\ folder not any sub-folder below that (lots in my case, see image). This would exclude the Framework folder, files and sub-folders "C:\Windows\Microsoft.NET\Framework\*"
That said why would you want to do this as it could be introducing a hole in your security.
As Igor asks, I suspect that you are checking on-demand scan logs and the file system shield, exclusions don't cover on-demand scans (avastUI, Settings, Exclusions).