the verdict to sandbox BTHelpBrowser.exe is based on a set of criteria(s) as in the screenshot.
notice that the reason u quoted from autosandbox is 'the file prevalence/reputation is low'
filerep is a new feature in Avast! v7 which provides prevalence/reputation analysis on the files u download/already have on ur system.
it affects the verdict to sandbox the executable or not.
apparently, BTHelpBrowser.exe is not well recognised in Avast community, thus being sandboxed as a precaution to potential malware.
when sufficient (i dunno how much) users have executed BTHelpBrowser.exe, Avast would decide whether to release BTHelpBrowser.exe from sandbox based on the behaviour that it performed on users' systems.
however, if ur sure that BTHelpBrowser.exe is safe, u can exclude BTHelpBrowser.exe from being sandboxed by selecting 'open normally' from the drop-down box of the blue autosandbox pop-up.
alternatively, u can manually exclude it from autosandbox via Avast GUI (additional protection -> autosandbox -> settings -> browse for BTHelpBrowser.exe to exclude it)