You then refer to "HotPopmail" which only (as far as Google searches go) leads to a pornographic website.
PopHotmail and not HotPopmail

Avast! 4.5 says very clearly that "no special setup" is required for scanning POP email. It seems that a number of us (Andyslogos for example) are using our email clients set to read POP3 mail where the mail server is localhost and the port is 110. The mail client is very successfully reading that POP3 mail but Avast! is NOT scanning this mail for us.
I would appreciate knowing if anyone has successfully used Avast! 4.5 to scan email being received via localhost and port 110.
Any guidance on how to further investigate or alleviate the problem would be most welcome too.
Sorry, I can't help you more as you can see...

I think that this is by design.
In 4.1 worked this way: mail server > spam killer or email popup > avast > mail client
In 4.5, on contrary, this way: mail server > avast > spam killer or email popup > mail client
So, I don't know why avast is not scanning your email.