If you exclude it from autosandboxing, it won't be autosandboxed, but it will still be scanned.
A full exclusion will exclude it even from scanning - so if it gets infected, it will be executed without being stopped.
Igor, can you check this plugin?
There are other users in the Portuguese forum that are complaining about this a lot.
I can translate your info to them 
Igor, you solved the problem! I just excluded it from autosandbox and now everything is alright. Thanks a lot man! This bug was bothering me a lot.