You didn't say why they couldn't be scanned which is also important.
There are many legitimate reasons why a file/s can't be scanned (password protected, corrupt archive, etc.).
If you have searched the avast forums you will see many such instances and essentially they are just files that can't be scanned, not that they are infected/suspicious, just that they can't be scanned and why.
Both of these factors file Location and why they can't be scanned to determine if it is legit.