Same issue here.
Avast 5 was freezing patchmix DSP at startup (it would only load after a couple of minutes), but version 6's behavior shield completely blocks the application AND the drivers. And it shows constant activity on the monitor.
Check the C:\ProgramData\Alwil(Avast) Software\Avast(5)\report\behaviorshield.txt file using notepad and check for any entries relating to the effected software. If there is try adding (copy and paste) the full path into the BehS, Expert Settings, Trusted processes and see if that helps, you may need to reboot.
Note - The text in the path within the brackets above may or may not be the option as both locations are valid depending on how you installed/updated to avast 6.0.
Something else you can try if the above doesn't work:
New Behaviour Shield, Expert settings option - 'monitor the system for unauthorised modifications' - this appears to be causing some applications not to start, presumably they modify the system in some way when they start.