Thanks for the support on this Erroneus and MICAH. The pop-up itself isn't so much the issue as the positioning of it. Like Erroneus said, it gets in the way. This should either display in a corner where it's out of the way, or be a toggle so you can turn it off. The example pic I attached previously was an especially annoying example as even the little icon, before the pop-over image displays, is covering up text.
Edit: Not to mention, I still have the tab open displaying that page with the pop-over, and it's bugged. The pop-over will NOT disappear, even when I mouse over another link that should trigger it.