In my opinion installing Comodo firewall is useless, because Windows have integrated firewall. On Windows Vistas and 7s the firewall is good. On the default settings incoming connection is prohibited and outcoming connection is allowed. This is very good setting for most users. No ask, firewall is silent.
Web Of trust (WOT) - this is good, but in the Internet Explorer takes up enough space alike avast! WebRep. WOT is equally avast! WebRep.
Side by side avast! I prefer to install Spybot Search&Destroy or Spyware Blaster becausethese antispywares protect Internet Explorer and Mozilla firefox and Opera against danegous cookies, domains, etc. And your homepage is lock by hijack-attack. If you install lot of freeware programs, google , ASK, Yahoo! and many companies impose their fuck programs, for example toolbars, search services, etc. And change your homepage. This is irritaing.
But the most important is early install updates for Windows and many programs (princippaly Adobe's programs). This is first defense.