Well, I'd stay away from ProcessGuard... I've seen way too many (hard-to-track) problems with this program. Just my €0.02 worth.
i will concur this time ... full version of Process Guard 3.150 is more stable than e.g. Kerio 4.2.x and theirs "HIPS"
(bsods caused by KPF in past years on my test systems goes to hundreds but since they start to experiment with various injection preventions it turned worse
to be fair to PG ... after i finally was able configure it right and understood how and what exactly define ... i have zero compatibility problems (usually any stability problem is caused by another software or drivers (e.g. abnormal hooking methods or accesses to memory))
there are some drawbacks when someone uses PG ...
first ... if You are not SKILLED person in Windows OS usage ... then forget about it it ...
second ... if You refuse to read PG manuals, FAQs and forums ... then forget about using it
also PG is not for gamers !...
anticheat solution PunkBuster for now refuse users with PG to join PB protected games (for obvious reason as it was used to hide cheats and prevent PB to operate)
PG is good software but only for users who really uderstood what it does ...so there is not much similar application to Process Guard
but i will suggest to take look at System Safety Monitor or Tiny Firewall 2005
there are of course more but these 3 are good start ...