"A COM class is an implementation of a group of interfaces in code executed whenever you interact with a given object. ... COM uses this CLSID, at the request of a client, to associate specific data with the DLL or EXE containing the code that implements the class, thus creating an instance of the object."
So I'd assume that the DLL or EXE in this case is perhaps a protected system file and you'd would indeed, as Eddy has just indicated, need the correct permissions to be able to delete it. CCleaner must have System permission already to delete a lot of the stuff it does so that suggests it may be or is associated with an system important file so you'd be pretty stupid to do anything without knowing more about it.
I've not had anything similar happen with the CCleaner's registry cleaner but if it were me I'd have run Chkdsk (both options ticked) and SFC (System File Checker) before even thinking about messing around with the regedit.
But, like others here have said, I wondered what on earth has anything about this matter to do with AVAST.
Then I Googled and quite a few references associate AVAST with this particular CLSID and the information actually comes from a tool used through this forum for fixing problems: the Farbar Recovery Scan Tool.
The example I found is actually from the Malwarebytes forum:-
https://forums.malwarebytes.com/topic/166808-system-hijack/#comment-956847the specific section of the Farbar scan referenced is under System Errors:-
Error: (03/31/2015 08:24:12 AM) (Source: DCOM) (EventID: 10005) (User: )
Description: 1053AvastVBoxSvc{F319F1B8-7587-4146-AF9C-0D6D77819BF1}The experts here can make of this what they will but it does suggest the problem, such as it is, might actually be AVAST related.
