Whilst I don't have the server edition, I see this on the avast4Home/Pro forum.
From this '(twthzyf.exe 64.156.215.18.25)' it would appear that you may have some form of email spambot installed trying to send email. Or as has happened with a P2P program communicating using an email port that would also cause a timeout.
A google search for twthzyf.exe doesn't return any hits and this makes me suspicious that this is more likely to be a spambot.
Do you have outbound firewall protection, if so I suggest as a temporary measure block twthzyf.exe.
Do you know this exe file 'twthzyf.exe' and what program it is associated with.
What OS is your server running ?
I'm not sure if you can run Ewido (best from safe mode) then download and run it
Ewido Security Suite If using winXP. I don't know if this can run on a server OS though.
Sorry I can't be of more help, hopefully someone more knowledgeable on the Server edition can help. I'm just about to turn in for the night, after midnight here.